Table 2.
Up regulated claudins in various cancers
| Cancer | Claudin gene | Expression | References |
|---|---|---|---|
| Breast | CLDN3 | Up | 13 |
| CLDN4 | Up | 13 | |
| Hepatocellular carcinoma | CLDN10 | Up | 14 |
| Squamous cell carcinoma | CLDN1 | Up | 15 |
| CLDN4 | Up | 15 | |
| Ovarian | CLDN3 | Up | 16,17, 18, 19 |
| CLDN4 | Up | 16, 18, 19 | |
| CLDN16 | Up | 20 | |
| Pancreatic | CLDN4 | Up | 21, 22,23,24 |
| Pancreatic (intraductal papillary mucinous neoplasms) | CLDN4 | Up | 25 |
| CLDN18.2 | Up | ||
| Prostate | CLDN3 | Up | 26 |
| CLDN4 | Up | 26 | |
| Thyroid papillary cancer | CLDN10 | Up | 27 |
| Endometrial Cancer | CLDN4 | Up | 28 |
| Oesophageal tumour | CLDN18.2 | Up | 29 |
| non-small cell lung cancer: Squamous cell carcinoma | CLDN1 | Up | 30 |
| Adenocarcinoma | CLDN4 | Up | 30 |
| CLDN5 | Up |