Table 1.
Characteristics of the patient sample.
| Demographic and clinical data | |
|---|---|
| Number | 72 |
| Male:Female | 42:30 |
| LRP-1 C667T genotype CC:CT:TT | 57:14:1 |
| ApoE ε 4 alleles: 0:1:2 | 29/28/15 |
| Age at PET: mean ± SD (range) | 69.2 ± 7.86 (50–84) |
| MMSE: mean ± SD (range) | 24.7 ± 3.77 (11–30) |
| CDR SOB: mean ± SD (range) | 3.34 ± 2.126 (0.5–10.0) |
| [11C]PiB uptake ratios (C/cv): mean ± SD (range) | 1.77 ± 0.347 (1.0–2.4) |
ApoE ε4: apolipoprotein E epsilon 4; CDR-SOB: clinical dementia rating sum of boxes; C/cv: cerebral to cerebellar vermis; LRP-1: low density lipoprotein receptor-related protein 1; MMSE: Mini-Mental State Examination; PiB: Pittsburgh compound B; ROI: region of interest; and SD: standard deviation.