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. Author manuscript; available in PMC: 2014 Mar 3.
Published in final edited form as: Methods Mol Med. 2005;107:69–95. doi: 10.1385/1-59259-861-7:069

Fig. 2.

Fig. 2

Morphology of human articular chondrocytes grown in monolayer culture on plastic. Chondrocytes were isolated from articular cartilage and cultured in DMEM/F12 containing 10% FCS until confluent and then subcultured and grown again to confluence. (a) Primary chondrocytes display the characteristic cobblestone morphology. (b) Passaged chondrocytes display features of a dedifferentiated phenotype, including a portion of cells with fibroblast-like morphology.