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. 2014 Feb 26;9:42. doi: 10.1186/1746-1596-9-42

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Copyright © 2014 Tian et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Immunohistochemical staining of AKR1C3 in human prostatic needle biopsies. (A) Normal prostate. (B) BPH. (C) PIN. (D) PBS negative control of prostate cancer tissue. (E)-(H) Different GS prostate cancer tissues. (E) Gleason score = 6. (F) Gleason score = 7. (G) Gleason score = 8. (H) Gleason score = 9. (I) The quantification bar for the MOD of AKR1C3. *P < 0.05, compared with BPH. ^#P < 0.05, compared with PIN. Scale bar is 50 μm.