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. Author manuscript; available in PMC: 2014 Jun 15.
Published in final edited form as: J Immunol. 2013 May 6;190(12):5927–5938. doi: 10.4049/jimmunol.1203202

Figure 6. Transfer of CD68enr/Df-lung-cells into DC-sensitized WT or Pla2g5-null recipient mice amplifies Df-induced pulmonary inflammation through chemokine-induced T-cell recruitment.

Figure 6

(A) Total cell and differential cell counts from BAL fluid of WT and Pla2g5-null recipient mice that were sensitized at day 0 with WT Df-BMDCs. At day 8, CD68enr/Df-lung-cells were transferred intratracheally At days 9 and 12 mice were challenged with Df or saline intranasally (DC + saline, DC + Df or DC + CD68enr/Df-lung-cells+ Df). Mice were euthanized 36 h after the last dose (inset). (B) ELISA measurement of CCL22 and CCL17 released in BAL fluid. (C) Lung CD4+ cell counts evaluated by flow cytometry. Values are mean ± SEM of three independent experiments with 10–23 mice per group. *, p<0.05; **, p<0.03; #, p<0.001