TABLE 4.
No. | Age, years |
Tumor Site | Stage | Primary Treatment |
Adjuvant Treatment | Treatment for Recurrence |
Status at Last Follow-up |
---|---|---|---|---|---|---|---|
1 | 17.8 | Cervix | IB1 | Cone biopsy | Vincristine, dactinomycin, and cyclophosphamide |
NA | NED 23 mo after completion of therapy |
2 | 12.5 | Cervix | IB2 | Cone biopsy | Vincristine, dactinomycin, and cyclophosphamide |
NA | NED 6 mo after completion of therapy |
3 | 33.3 | Cervix | IB1 | TAH and BSO | Cisplatin and doxorubicin. Treated immediately after surgery with whole- pelvic and intracavitary vaginal radiation to 45 Gy |
Chemotherapy | Dead of complications related to neutropenic fever |
4 | 49.3 | Cervix and lower uterine segment |
IB1 | TAH and BSO | Cyclophosphamide, doxorubicin, vincristine, and dacarbazine. Radiation beginning 6 mo after diagnosis: 46 Gy delivered over 31 days |
NA | Dead of parotid adenocarcinom a |
5 | 51.9 | Cervix | IB2 | Cone biopsy | NA | NA | NED 19 mo after completion of therapy |
6 | 2.9 | Cervix and midposteri or vagina |
IIA | Polypectomy | Vincristine, dactinomycin, and cyclophosphamide |
NA | NED 35 mo after completion of therapy |
7 | 12.7 | Endocervix extending to vagina |
IB2 | VAC | TAH | NA | NED 121 mo after completion of therapy |
8 | 17.3 | Cervix | NA | Cone biopsy | Vincristine, doxorubicin, and cyclophosphamide |
Refused chemotherapy |
Dead of disease |
9 | 34.2 | Cervix | NA | VAC, FAC | Cone biopsy | Not known whether patient had recurrence |
Dead of unknown cause |
10 | 27.2 | Cervix | IB2 | Cone biopsy | NA | Refused chemotherapy |
Alive with disease |
11 | 18.4 | Cervix | IB1 | Cone biopsy, diagnostic laparoscopy |
Vincristine, dactinomycin, and cyclophosphamide |
NA | NED 4 mo after completion of therapy |
NA, Not applicable – patient did not have recurrence; NED, no evidence of disease; TAH; total abdominal hysterectomy; BSO, bilateral salpingo-oophorectomy; VAC, vincristine, dactinomycin, and cyclophosphamide; FAC, fluorouracil, doxorubicin, and cyclophosphamide.