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. Author manuscript; available in PMC: 2014 Mar 3.
Published in final edited form as: Mucosal Immunol. 2010 Oct 13;4(1):22–30. doi: 10.1038/mi.2010.61

Figure 1.

Figure 1

ATM-dependent checkpoint responses and apoptosis triggered by H. hepaticus CDT-induced DNA damage 75, 76. DSB, double strand breakage; Nbs 1, Nijmegen Breakage Syndrome 1 protein; ATM, Ataxia Telangiectasia Mutated; CHK2, checkpoint kinase 2; Bcl2, B-cell leukemia/lymphoma 2; Bax, Bcl-2–associated X protein; Cyt c, Cytochrome c; Apaf-1, apoptotic peptidase activating factor 1.