Table 2.
Summary of ROC Analysis for 1-Year Death/HTx/LVAD Requirement Stratified According to Anticoagulation Treatment
| Total Patients (N = 260) |
Patients on Anticoagulation (n = 104) |
Patients off Anticoagulation (n = 156) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Variable | AUC | Sensitivity (%) | Specificity (%) | p Value | AUC | Sensitivity (%) | Specificity (%) | p Value | AUC | Sensitivity (%) | Specificity (%) | p Value |
| MELD | 0.71 | 80.5 | 57.6 | <0.0001 | 0.55 | 39.1 | 76.5 | 0.1823 | 0.81 | 76.5 | 84.2 | 0.0001 |
| MELDNa | 0.73 | 95.1 | 46.0 | <0.0001 | 0.55 | 21.7 | 92.6 | 0.1752 | 0.84 | 94.1 | 64.8 | <0.0001 |
| MELD-XI | 0.69 | 62.5 | 65.9 | 0.0002 | 0.61 | 73.9 | 50.6 | 0.0740 | 0.77 | 64.7 | 84.2 | 0.0005 |
| Creatinine | 0.62 | 53.7 | 69.6 | 0.5162 | 0.60 | 60.9 | 61.7 | 0.1021 | 0.66 | 64.7 | 73.4 | 0.9068 |
| Total bilirubin | 0.66 | 48.8 | 74.1 | 0.0323 | 0.59 | 65.2 | 51.9 | 0.7316 | 0.71 | 47.1 | 92.8 | 0.0154 |
| INR | 0.70 | 92.5 | 55.5 | 0.0111 | 0.52 | 17.4 | 6.17 | 0.3442 | 0.84 | 82.4 | 82.7 | 0.1682 |
| Serum sodium | 0.64 | 61.0 | 62.5 | 0.0158 | 0.59 | 100 | 16.5 | 0.2893 | 0.68 | 70.6 | 65.4 | 0.0386 |
AUC = area under the curve; HTx = heart transplantation; LVAD = left ventricular assist device; MELD = Model for End-Stage Liver Dysfunction; MELDNa = MELD serum sodium score; MELD-XI = MELD without INR; ROC = receiver-operating characteristic; other abbreviations as in Table 1.