Table 3. List of adverse events.
Each adverse event is listed, including number of patients experiencing that event and grade.
| AE Description | Grade 1 | Grade 2 | Grade 3 | Grade 4/5 | Total # with serious AE (grades 3–5) |
|---|---|---|---|---|---|
| Abdominal Pain | 2 | 1 | 1 | ||
| Fever | 1 | 0 | |||
| Fatigue | 2 | 1 | 0 | ||
| Lower Extremity Edema | 2 | 1 | 1 | ||
| Urinary Retention | 1 | 0 | |||
| Elevated AST | 1 | 1 | |||
| Dyspnea | 2 | 0 | |||
| Pain (Back, Pelvis, Leg) | 1 | 0 | |||
| Constipation | 1 | 0 | |||
| Xerostomia | 1 | 0 | |||
| Vomiting | 1 | 0 | |||
| Tremor | 1 | 1 | 0 | ||
| Pulmonary Embolus | 1 | 1 | 2 | ||
| Nausea | 1 | 0 | |||
| Candidiasis | 2 | 0 | |||
| Disequilibrium | 2 | 0 | |||
| Lower Extremity Coldness | 1 | 0 | |||
| Tumor Pain | 1 | 0 | |||
| Seizures* | 1 | 0 | |||
| Hyponatremia | 1 | 1 | |||
| Volume Depletion | 1 | 1 | |||
| Sudden Death | 1 | 1 |
*
Seizures likely due to new brain metastases and not DCA