Table 5.
Adjusted percent change in heart rate variability (log) associated with IQR increases of 7-day moving averages of PM2.5 and black carbon by gene polymorphisms
| Heart rate variability | Isoform | PM2.5 % change (95% CI) |
Black carbon % change (95% CI) |
|
|---|---|---|---|---|
| GSTT1 | High frequency | Deletion | 1.46 (−11.49 – 14.46) | −6.44 (−30.29 – 17.39) |
| High frequency | Non-Deletion | −3.74 (−11.54 – 4.01) | −1.33 (−16.01 – 13.35) | |
| HFE (rs1800562) | High frequency | Wild | −2.55 (−9.80 – 4.70) | −5.59 (−19.10 – 7.92) |
| High frequency | Non-Wild | 0.59 (−14.09 – 15.28) | 9.02 (−20.80 – 38.84) | |
| GSTT1 | Low frequency | Deletion | 0.36 (−10.58 – 11.31) | −13.61 (−33.88 – 6.67) |
| Low frequency | Non-Deletion | −1.32 (−7.89 – 5.29) | 0.95 (−11.53 – 13.44) | |
| HFE (rs1800562) | Low frequency | Wild | −1.23 (−7.34 – 4.88) | −6.02 (−17.48 – 5.44) |
| Low frequency | Non-Wild | 0.41 (−12.08 – 12.95) | 7.97 (−17.27 – 33.20) | |
| GSTT1 | Standard deviation of normal-to-normal intervals | Deletion | 1.23 (−4.38 – 6.84) | −3.83 (−14.4 – 6.740) |
| Standard deviation of normal-to-normal intervals | Non-Deletion | −1.73 (−5.11 – 1.64) | −2.94 (−9.37– 3.51) | |
| HFE (rs1800562) | Standard deviation of normal-to-normal intervals | Wild | −1.46 (−4.61 –1.69) | −5.35 (−11.26– 0.55) |
| Standard deviation of normal-to-normal intervals | Non-Wild | 1.41 (−5.15 – 7.93) | 4.48 (−8.54 – 17.50) |
Interquartile ranges (IQR) of 7-day moving averages of PM2.5 and BC were 4.56 and 0.49 μg/m3, respectively.