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. Author manuscript; available in PMC: 2014 Mar 3.
Published in final edited form as: Mol Imaging Biol. 2013 Aug;15(4):423–430. doi: 10.1007/s11307-013-0614-2

Figure 2.

Figure 2

Fluorescence intensity (in relative fluorescence units) for ROIs selected from the lower limbs of mice at given timepoints after intravenous injection of LS601-PEG40 (n=3 mice). Based upon our results (see Results section), which indicate the free dye clears from injured control animals within 4 hours, attachment to PEG40 does result in significantly higher circulation times within which detection of ROS could take place. The fluorescence intensity increased about 2-fold in the injured limb over 24 hr. Bars indicate standard deviation and (*) indicates statistically significant (P<0.01) differences.