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. Author manuscript; available in PMC: 2014 Mar 3.
Published in final edited form as: Psychoneuroendocrinology. 2011 Feb 12;36(7):1053–1061. doi: 10.1016/j.psyneuen.2011.01.003

Table 3.

The association of candidate gene SNPs with cortisolAUC

SNP
Most
significant		 No.
Significant		 Gene Chr. Variant MAF beta se p-value unadj. p-value adj. a
cortisolAUC (nmol/L)
rs9470080 4 FKBP5 6 G > A 0.34 −0.55 0.12 1.0e-05 0.001
rs11152221 - MC4R 18 G > A 0.32 −0.36 0.12 3.1e-03 0.18
rs2284218 - CRHR2 7 A > G 0.36 0.34 0.12 5.6e-03 0.35
rs2296236 - AVP 20 G > A 0.16 −0.44 0.16 7.1e-03 0.40
rs7735244 - SRD5A1 5 A > G 0.10 −0.50 0.19 9.6e-03 0.44
rs10519942 - NR3C2 4 G > A 0.07 0.59 0.23 0.009 0.48
rs6672903 - HSD3B2 1 A > G 0.44 0.30 0.12 0.012 0.59

Abbreviations: SNP, single nucleotide polymorphism; Chr., Chromosome; MAF, minor allele frequency; se, standard error

a

adjusted for multiple testing using max (T) permutation (10.000).