| Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
| Adverse effects | |||||
|
RCT |
75 people; 75 eyes with rhegmatogenous retinal detachment (RRD) and grade C proliferative vitreoretinopathy (PVR) |
Intraocular pressure
6 months
14.7 mmHg with triamcinolone acetonide 16.4 mmHg with no triamcinolone acetonide |
P = 0.25 |
Not significant | |
|
RCT |
75 people; 75 eyes with RRD and grade C PVR |
Recurrence of PVR
6 months
11/38 (29%) with triamcinolone acetonide 11/37 (37%) with no triamcinolone acetonide |
P = 0.94 |
Not significant | |
|
RCT |
75 people; 75 eyes with RRD and grade C PVR |
Macular pucker
6 months
8/38 (21%) with triamcinolone acetonide 13/37 (35%) with no triamcinolone acetonide |
P = 0.2 |
Not significant | |
|
RCT |
220 people with RRD (220 consecutive eyes) having sclera buckling procedure plus air or SF6 gas in around 50% of eyes plus primary vitrectomy in around 14% of eyes; posterior Nd:Yag capsulotomy in around 9% of eyes; 79.5% phakic |
Post-operative PVR stage A
at 1 month
5/106 (5%) with oral prednisone tapering for 15 days 7/99 (7%) with placebo |
Reported as not significant |
Not significant | |
|
RCT |
220 people with RRD (220 consecutive eyes) having sclera buckling procedure plus air or SF6 gas in around 50% of eyes plus primary vitrectomy in around 14% of eyes; posterior Nd:Yag capsulotomy in around 9% of eyes; 79.5% phakic |
Post-operative PVR stage B
at 1 month
28/106 (26%) with oral prednisone tapering for 15 days 40/99 (40%) with placebo |
P <0.05 |
Effect size not calculated | prednisone |
|
RCT |
220 people with RRD (220 consecutive eyes) having sclera buckling procedure plus air or SF6 gas in around 50% of eyes plus primary vitrectomy in around 14% of eyes; posterior Nd:Yag capsulotomy in around 9% of eyes; 79.5% phakic |
Post-operative PVR stage C
at 1 month
5/106 (5%) with oral prednisone tapering for 15 days 3/99 (3%) with placebo |
Reported as not significant |
Not significant | |
|
RCT |
220 people with RRD (220 consecutive eyes) having sclera buckling procedure plus air or SF6 gas in around 50% of eyes plus primary vitrectomy in around 14% of eyes; posterior Nd:Yag capsulotomy in around 9% of eyes; 79.5% phakic |
Post-operative PVR stage A
at 3 months
6/107 (6%) with oral prednisone tapering for 15 days 4/99 (4%) with placebo |
Reported as not significant |
Not significant | |
|
RCT |
220 people with RRD (220 consecutive eyes) having sclera buckling procedure plus air or SF6 gas in around 50% of eyes plus primary vitrectomy in around 14% of eyes; posterior Nd:Yag capsulotomy in around 9% of eyes; 79.5% phakic |
Post-operative PVR stage B
at 3 months
27/107 (25%) with oral prednisone tapering for 15 days 45/99 (46%) with placebo |
P <0.005 |
Effect size not calculated | prednisone |
|
RCT |
220 people with RRD (220 consecutive eyes) having sclera buckling procedure plus air or SF6 gas in around 50% of eyes plus primary vitrectomy in around 14% of eyes; posterior Nd:Yag capsulotomy in around 9% of eyes; 79.5% phakic |
Post-operative PVR stage C
at 3 months
3/107 (3%) with oral prednisone tapering for 15 days 2/99 (2%) with placebo |
Reported as not significant |
Not significant | |
|
RCT |
220 people with RRD (220 consecutive eyes) having sclera buckling procedure plus air or SF6 gas in around 50% of eyes plus primary vitrectomy in around 14% of eyes; posterior Nd:Yag capsulotomy in around 9% of eyes; 79.5% phakic |
Post-operative PVR stage A
at 6 months
1/102 (1%) with oral prednisone tapering for 15 days 4/94 (4%) with placebo |
Reported as not significant |
Not significant | |
|
RCT |
220 people with RRD (220 consecutive eyes) having sclera buckling procedure plus air or SF6 gas in around 50% of eyes plus primary vitrectomy in around 14% of eyes; posterior Nd:Yag capsulotomy in around 9% of eyes; 79.5% phakic |
Post-operative PVR stage B
at 6 months
23/102 (23%) with oral prednisone tapering for 15 days 43/94 (46%) with placebo |
P <0.0005 |
Effect size not calculated | prednisone |
|
RCT |
220 people with RRD (220 consecutive eyes) having sclera buckling procedure plus air or SF6 gas in around 50% of eyes plus primary vitrectomy in around 14% of eyes; posterior Nd:Yag capsulotomy in around 9% of eyes; 79.5% phakic |
Post-operative PVR stage C
at 6 months
2/102 (2%) with oral prednisone tapering for 15 days 3/94 (3%) with placebo |
Reported as not significant |
Not significant |