Table 1.
Clinical and demographic characteristics of patients.
| Parameter | Patients screened (n = 187) | Patients enrolled (n = 102) | MHEa (n = 41) | NMHEa (n = 61) |
|---|---|---|---|---|
| Sex (Male)b | 168 (89.8%) | 89 (87.3%) | 37 (90.2%) | 52 (85.2%) |
| Age (in years)c | 47.57 (45.90–49.24) | 45.68 (43.38–47.97) | 46.68 (42.80–50.57) | 45 (42.11–47.89) |
| CTP Classb | ||||
| Class A | 71 (38.0%) | 54 (52.9%) | 16 (39%) | 38 (62.3%) |
| Class B | 74 (39.6%) | 35 (34.3%) | 16 (39%) | 19 (31.1%) |
| Class C | 42 (22.5%) | 13 (12.7) | 9 (22%) | 4 (6.6%) |
| MELD scorec | 13.26 (12.53–13.98) | 11.96 (11.06–12.87) | 13.29 (11.78–14.80) | 11.07 (9.97–12.17) |
| Etiologyb | ||||
| Alcohol | 120 (64.2%) | 52 (51%) | 23 (56.1%) | 29 (47.6%) |
| HBV | 22 (11.7%) | 15 (14.7%) | 9 (22.1%) | 6 (9.8%) |
| HCV | 13 (7%) | 9 (8.8%) | 4 (9.6%) | 5 (8.3%) |
| Others | 32 (17.1%) | 26 (25.5%)d | 5 (12.2%) | 21 (34.3%) |
| Education in yearsc | 11.17 (10.61–11.73) | 12.22 (11.67–12.76) | 12.39 (11.60–13.18) | 12.10 (11.34–12.86) |
CTP, Child–Turcotte–Pugh; HBV, hepatitis B virus; HCV, hepatitis C virus; MHE, minimal hepatic encephalopathy; NMHE, non-minimal hepatic encephalopathy.
a
MHE and NMHE columns describe patients who have been enrolled; distinction between the 2 groups was based on the results of psychometric hepatic encephalopathy score.
b
Number (percentage).
c
Mean (95% confidence interval).
d
Non-alcoholic steatohepatitis 5 patients, autoimmune hepatitis 5, and cryptogenic cirrhosis in 14 patients.