Table 2.
Hazard ratios for all-cause, cardiovascular and liver mortality comparing elevated (>51 U/L in men and >30 U/L in women) gamma-glutamyltranspeptidase (GGT) versus normal GGT.
| N | Normal GGT | Elevated GGT HR (95% CI) | P value | |
|---|---|---|---|---|
| All-cause mortality | ||||
| Age-sex adjusted | 2364 | Referent | 1.67 (1.35–2.06) | <.0001 |
| Multivariatea-adjusted | 1790 | Referent | 1.55 (1.21–1.98) | .0005 |
| CVD mortality | ||||
| Age-sex adjusted | 2364 | Referent | 1.71 (1.26–2.32) | .0006 |
| Multivariate-IL-6 adjusted | 1790 | Referent | 1.51 (1.04–2.17) | .0289 |
| Liver disease mortality | ||||
| Age-sex adjusted | 2364 | Referent | 9.05 (4.04–20.27) | <.0001 |
| Multivariatea-adjusted | 1790 | Referent | 9.10 (3.42–24.26) | <.0001 |
HR; hazards ratio, CI; confidence interval.
A two-tailed p-value of less than .05 was considered statistically significant.
a
Multivariate-model includes age-sex-alcohol-BMI-Total cholesterol-HDL cholesterol-serum triglyceride-smoking-systolic blood pressure-diabetes mellitus, IL-6 and CRP.