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. 2014 Feb 14;11:30. doi: 10.1186/1743-422X-11-30

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Copyright © 2014 Tian et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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CRTC2 enhances HBV transcription. (A) Luciferase activity in Huh-7 cells transfected with pGL-3-ENII-luc and p-CRTC2. (B) HBV mRNA levels in Huh-7 cells transfected with 1.3× wtHBV plasmid and p-CRTC2. (C-D) The effect of CRTC2 knock down on luciferase activity (C) and HBV mRNA levels (D) in pGL-3-ENII-luc and 1.3× wtHBV plasmid-transfected Huh-7 cells, respectively. *p < 0.05.