Table 1.
Characteristic | Cases n = 128 | Controls n = 269 | p value |
---|---|---|---|
Date of birth (mean) (range) | 1965.2 (1947–82) | 1964.5 (1946–81) | 0.44 |
Year of diagnosis (range) | 1997.3 (1985–2009) | 1997.8 (1985–2011) | 0.47 |
Age of breast cancer (range) | 32.5 (25–42) | 33.8 (26–44) | 0.009 |
Date of baseline questionnaire (range) | 2,003.5 (1996–2011) | 2,003.7 (1996–2012) | 0.84 |
Mutation n (%) | |||
BRCA1 | 106 (81.3 %) | 227 (84.4 %) | Matched |
BRCA2 | 24 (18.8 %) | 42 (15.6 %) | |
Place of residence | 96 (75.0 %) | 210 (78.1 %) | Matched |
North America | 20 (15.6 %) | 43 (16.0 %) | |
Poland | 12 (9.4 %) | 16 (6.0 %) | |
Others | |||
Parous | |||
No | 0 | 78 (29.5 %) | 0.62 |
Yes | 128 (100 %) | 191 (71.0 %) | |
Mean Parity | 2.1(1–5) | 2.0 (1–4) | |
Age of menarche (years) | 12.8 (9–17) | 12.8 (10–21) | 0.73 |
Age at first birth (years) | 30.7 (18–42) | 25.6 (18–33) | < 0.0001 |
Age at last birth (years) | 35.0 (27–44) | 28.7 (20–38) | < 0.0001 |
Time from diagnosis to last childbirth (years) | 2.4 (0–13) | NA | < 0.0001 |
Salpingo-oophorectomy after breast cancer diagnosis | |||
No | 55 (43.0 %) | 127 (47.2 %) | |
Yes | 73 (57.0 %) | 142 (52.8 %) | 0.43 |
Vital status | |||
Alive | 120 (92.8 %) | 246 (91.5 %) | |
Dead | 8 (6.3 %) | 23 (8.6 %) | 0.42 |
Cause of death | |||
Breast cancer | 7 | 19 | |
Unknown | 1 | 4 |