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. Author manuscript; available in PMC: 2014 Mar 3.
Published in final edited form as: Cancer Res. 2011 Feb 17;71(7):2611–2621. doi: 10.1158/0008-5472.CAN-10-3666

Figure 4. Transient transfection of miR-205 inhibits renal cancer cell proliferation, colony formation, migration, invasion, and induces apoptosis and cell cycle arrest in A498 cells.

Figure 4

A) Proliferation of A498 cells after miR-205 transfection was significantly reduced compared to cont-miR. B) miR-205 overexpression significantly inhibits colony formation of A498 cells. C) Wound healing and migration assays of A498 cells transfected with miR-205. D) Invasion assay shows a significant decrease in the number of invading A498 cells transfected with miR-205. E) Cell cycle analysis showing an increase in the G0/G1 phase of A498 cells overexpressing miR-205. F) Apoptosis assay showing induction of apoptosis by miR-205. *p<0.05.