Table 2.
Demographic, clinical and laboratory parameters in all HCC patients and in patients of different etiologic groups.
| Parameters | All patients (n = 142) | Viral etiology (n = 83) | Alcohol etiology (n = 31) | Cryptogenic etiology (n = 26) | Miscellaneous etiology (n = 2) |
|---|---|---|---|---|---|
| Age, yearsa,b | 60 (30–83) | 57 (30–77) | 61 (46–76) | 66 (54–83) | 56 (50–61) |
| Age groupb | |||||
| <50 years | 20 (14%) | 17 (21%) | 3 (10%) | 0 (0%) | 0 (0%) |
| 50–70 years | 106 (75%) | 60 (72%) | 24 (77%) | 20 (77%) | 2 (100%) |
| >70 years | 16 (11%) | 6 (7%) | 4 (13%) | 6 (23%) | 0 (0%) |
| Gender | |||||
| Males | 130 (92%) | 73 (88%) | 31 (100%) | 25 (96%) | 1 (50%) |
| Females | 12 (8%) | 10 (12%) | 0 (0%) | 1 (4%) | 1 (50%) |
| Diabetes mellitusb,c | 35 (25%) | 14 (17%) | 6 (19%) | 15 (58%) | 0 (0%) |
| Cirrhosisa | 126 (89%) | 69 (83%) | 31 (100%) | 24 (92%) | 2 (100%) |
| CTP scorea,c | 8 (5–14) | 7 (5–13) | 10 (6–14) | 8 (5–11) | 6 (6–7) |
| MELD scorea,c | 14 (6–36) | 13 (6–35) | 18 (8–36) | 12 (7–30) | 10 (10–11) |
| CTP classa,c | |||||
| A | 43 (30%) | 27 (33%) | 5 (16%) | 10 (38%) | 1 (50%) |
| B | 63 (45%) | 39 (47%) | 10 (32%) | 13 (50%) | 1 (50%) |
| C | 36 (25%) | 17 (20%) | 16 (52%) | 3 (12%) | 0 (0%) |
| Ascites | 83 (58%) | 48 (58%) | 21 (68%) | 14 (54%) | 0 (0%) |
| HE | 14 (10%) | 5 (6%) | 5 (16%) | 4 (15%) | 0 (0%) |
| Varices present | 60/79 (76%) | 34/45 (76%) | 14/16 (88%) | 11/17 (65%) | 1/1 (100%) |
| Bleedersa | 23 (16%) | 10 (12%) | 9 (29%) | 4 (15%) | 0 (0%) |
| Serum bilirubin, mg/dLa | 2.0 (0.3–31.6) | 1.9 (0.3–31.6) | 3.3 (0.6–20.0) | 1.7 (0.4–23.2) | 1.8 (0.7–3.0) |
| INRaˆ | 1.4 (0.9–4.6) | 1.4 (0.9–4.6) | 1.6 (1.0–3.2) | 1.3 (0.9–3.3) | 1.0 (1.0–1.1) |
| Serum albumin, g/dLa,c | 3.0 (1.3–4.9) | 3.1 (1.4–4.9) | 2.8 (1.3–4.0) | 3.2 (1.4–3.8) | 3.4 (2.9–3.8) |
| Hb, g/dL | 11.1 (5.4–16.7) | 11.2 (5.4–16.7) | 10.9 (6.5–16.2) | 10.4 (7.4–14.6) | 11.4 (11.0–11.8) |
| WBC, n/mm3 | 6.4 (1.0–27.5) | 6.3 (1.0–22.4) | 6.5 (2.7–27.5) | 6.7 (2.8–15.2) | 5.2 (4.3–6.0) |
| Platelets, n×103/mm3 | 109 (15–740) | 109 (20–680) | 109 (15–740) | 114 (35–411) | 162 (88–235) |
| Serum creatinine, mg/dLa | 1.0 (0.4–5.0) | 1.0 (0.4–5.0) | 1.2 (0.5–2.6) | 1.0 (0.5–2.8) | 1.1 (1.0–1.3) |
Abbreviations: CTP, Child-Turcotte-Pugh; HE, hepatic encephalopathy.
Notes: All values are expressed in median (range) or number (%).
a
P < 0.05 for viral vs alcohol etiology.
b
P < 0.05 for viral vs cryptogenic etiology.
c
P < 0.05 for alcohol vs cryptogenic etiology.