Table 4.
Demographic, clinical and laboratory parameters in HCC patients of HBV etiology (alone) compared with non-HBV etiologies.
| Parameters | HBV etiology (n = 49) | Non-HBV etiology (n = 86) | P value |
|---|---|---|---|
| Age, years | 56 (30–77) | 62 (42–83) | <0.01 |
| Age group | 0.013 | ||
| <50 years | 11 (22%) | 7 (8%) | |
| 50–70 years | 36 (74%) | 65 (76%) | |
| >70 years | 2 (4%) | 14 (16%) | |
| Gender | 0.352 | ||
| Males | 43 (88%) | 80 (93%) | |
| Females | 6 (12%) | 6 (7%) | |
| Diabetes mellitus | 8 (16%) | 26 (30%) | 0.099 |
| Cirrhosis | 36 (74%) | 84 (98%) | <0.01 |
| CTP score | 7 (5–13) | 8 (5–14) | 0.010 |
| MELD score | 13 (7–35) | 15 (6–36) | 0.193 |
| CTP class | 0.029 | ||
| A | 22 (45%) | 20 (23%) | |
| B | 18 (37%) | 40 (47%) | |
| C | 9 (18%) | 26 (30%) | |
| Ascites | 21 (43%) | 56 (65%) | 0.018 |
| HE | 2 (4%) | 12 (14%) | 0.084 |
| Varices present | 17/25 (68%) | 39/50 (78%) | 0.475 |
| Bleeders | 4 (8%) | 18 (21%) | 0.057 |
| Serum bilirubin, mg/dL | 1.8 (0.3–31.6) | 2.2 (0.4–23.2) | 0.118 |
| INR | 1.4 (0.9–3.2) | 1.4 (0.9–4.6) | 0.403 |
| Serum albumin, g/dL | 3.3 (1.4–4.9) | 2.9 (1.3–4.3) | 0.017 |
| Hb, g/dL | 10.7 (6.7–16.7) | 11.2 (6.5–16.2) | 0.849 |
| WBC, n/mm3 | 6.3 (1.0–22.4) | 6.4 (1.1–27.5) | 0.738 |
| Platelets, n × 103/mm3 | 110 (20–347) | 105 (15–740) | 0.891 |
| Serum creatinine, mg/dL | 0.9 (0.4–5.0) | 1.1 (0.5–2.8) | 0.099 |
Abbreviations: CTP, Child-Turcotte-Pugh; HE, hepatic encephalopathy.
Notes: All values are expressed in median (range) or number (%). Seven patients with mixed etiology involving HBV (i.e. HBV + HCV and HCV + ALD) were excluded from analysis.
Notes: All values are expressed in median (range) or number (%). Seven patients with mixed etiology involving HBV (i.e. HBV + HCV and HCV + ALD) were excluded from analysis.