Table 1. Antimicrobial susceptibility patterns of R. planticola KpNDM1, E. coli EcNDMneg, E. coli EcNDM1-4 and their transformants.
Antibiotics | Minimum inhibitory concentration (mg/L) | |||||
R. planticola | E. coli | E. coli | E. coli | E. coli | E. coli | |
RpNDM1 | EcNDM1 | EcNDMneg | EcNDMneg (4812) | JM109 (pEcNDM1-4) | JM109 | |
TZP | >256 | >256 | 16 | 32 | >256 | 0.75 |
CTX | >256 | >256 | >256 | >256 | >256 | 0.25 |
ATM | 0.094 | 32 | 32 | 32 | 0.064 | 0.064 |
GEN | 4 | 16 | 16 | 16 | 0.125 | 0.094 |
AMK | 3 | 6 | 6 | 6 | 1.5 | 0.5 |
CIP | 0.75 | >32 | >32 | >32 | 0.5 | 0.032 |
IMP | >32 | >32 | 0.19 | 16 | 16 | 0.19 |
MEM | >32 | >32 | 0.23 | 16 | 16 | 0.016 |
CST | 0.5 | 0.75 | 0.5 | 0.5 | 0.125 | 0.125 |
TGC | 0.75 | 0.38 | 0.38 | 0.38 | 0.38 | 0.25 |
MHT* | positive | positive | negative | positive | positive | negative |
TZP: piperacillin/tazobactam; CTX: cefotaxime; ATM: aztreonam; GEN: gentamicin; AMK: amikacin; CIP: ciprofloxacin; IPM: imipenem; MEM: meropenem; CST: colistin; TGC: tigecycline.
MHT*: Modified hodge test was performed and interpreted according to 2011 CLSI recommendation.