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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Biomech Model Mechanobiol. 2013 Jul 30;13(3):565–572. doi: 10.1007/s10237-013-0518-8

Figure 5.

Figure 5

Effects of MnTMPyP, rotenone, and cytochalasin B on stress-induced DHE staining. Sequestering superoxide produced significant reductions in DHE staining at both 0.5MPa and 0.25MPa (p<0.05). Inhibition of mitochondrial electron transport with rotenone decreased DHE staining after 1 hour of 0.25MPa static compressive stress (p<0.05). Cytoskeletal dissolution with cytochalasin B significantly decreased DHE staining at 0.25MPa (p<0.05). Statistical significance markers (p<0.05) are denoted as α indicating significance vs. 0.25MPa untreated specimens, β vs. 0.5MPa untreated specimens, γ vs. 0.5MPa rotenone treatment, and δ vs. 0.5MPa cytochalasin B treated.