Table 2.
Studies included: clinical summary
| Study | Predominant complaint | Duration of symptoms | History of trauma | History of infection | Family history | Treatment | Recurrence | Complications |
|---|---|---|---|---|---|---|---|---|
| De Berker and Langtry [9] | NR | 4–72 months | 0 | 0 | 0 | Excision/secondary intention | Yes x 2 | Distal onycholysis in 4 patients |
| De Palma et al. [10] | Pain | 4–32 months | NR | NR | NR | Excision | No | Partial onychodystrophy in 2 patients |
| Evison and Price [12] | NR | 1–18 months | 2/18 | 0 | 0 | Excision | Yes x 4 | Infection in 4 patients |
| Fikry et al. [13] | Pain | 21/28 | 0 | 0 | Excision | NR | NR | |
| Ippolito et al. [16] | Rest pain and walking pain | 1–48 months | 0 | NR | NR | Excision | No | Nail failed to regrow in 8 patients |
| Landon et al. [18] | Pain | 12 months | 9/39 | 15/39 | 0 | Excision, amputation in 1 patient | Yes x 5 | NR |
| Letts et al. [20] | Pain, enlarging nodule, ulceration | NR | 3/21 | 2/21 | 0 | Excision, amputation in 1 patient | Yes x 3 | Ingrown toenail in 2 patients, nail regrowing vertically |
| Li et al. [21] | Pain, nail deformity | 3–84 months | 3/20 | NR | 0 | Excision, amputation in 3 patients | Yes x 1 | NR |
| Miller-Breslow and Dorfman [26] | Pain in 5 patients, mass in 14 patients | 2 weeks to 10 years | 0 | 0 | 0 | Excision, amputation in 1 patient | Yes x 8 | Misdiagnosis in 3 patients, incomplete excision in 5 patients |
| Oliveira et al. [29] | Mass | NR | NR | NR | NR | Excision with “hammer and chisel” | Yes x 3 | NR |
| Ortega and Sanchez [30] | Pain in 15 patients | NR | 4/20 | NR | NR | Excision | NR | NR |
| Suga and Mukouda [34] | Pain | NR | 4/14 | 4/14 | NR | Excision, including partial nail bed in 9 patients | No | Onycholysis, ingrown toenail |
| Valinsky et al. [37] | Pain in all except 1, mass in all | NR | NR | NR | NR | Excision and dexamethasone | No | NR |
NR = not reported.