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. 2014 Mar 3;9(3):e90232. doi: 10.1371/journal.pone.0090232

Table 1. Concentrations (µmol/L) of the L-ornithine derived polyamines putrescine, spermidine and spermine in lung homogenates of naïve control and Pseudomonas infected mice treated with PBS or arginase inhibitor ABH.

Putrescine Spermidine Spermine
Control 4.9±1.2 * 4.0±1.2 * 2.6±0.7 *
Pseudomonas
PBS 34.2±2.4 39.6±2.3 13.6±0.8
ABH 28.7±2.9 37.5±3.7 12.5±0.8

* Concentrations were significantly different between groups (p<0.001, ANOVA). All three polyamines were lower in controls compared to infected animals but not different between PBS or ABH treatment group (n = 6–8/group).