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. 2014 Mar 3;9(3):e90232. doi: 10.1371/journal.pone.0090232

Table 2. Cytokine concentrations (ng/g) in lung homogenates of naïve control and Pseudomonas infected mice treated with PBS or arginase inhibitor ABH.

P. aeruginosa
Control (n = 6) PBS (n = 14) ABH (n = 15)
IFN-γ 0.04±0.01 * 3.50±0.83 2.54±0.52
IL-1β 8.54±0.96 15.51±3.02 12.26±2.37
IL-6 9.97±0.51 * 52.27±5.67 65.09±12.1
MIP-2 0.15±0.01 * 59.46±7.30 44.29±3.67
KC 4.52±1.43 * 31.84±5.90 29.28±3.58
TNF-α 0.05±0.01 * 7.61±1.41 5.48±0.83

Concentrations were significantly different between groups (p<0.001, Kruskal-Wallis test). All cytokines with the exception of IL-1β were lower in controls compared to infected animals not different between PBS and ABH treated animals.