Table 4. Univariate analysis of clinicopathologic features for overall survival of 78 patients with biliary tract cancer.
Characteristics | n | Survival rate (%) | P |
Gender | |||
Male | 34 | 54.3 | 0.693 |
Female | 44 | 53.5 | |
Age(year) | |||
<60 | 32 | 41.9 | 0.984 |
≥60 | 46 | 61.7 | |
TNM stage | |||
I | 10 | 54.5 | 0.365 |
II | 24 | 58.3 | |
III | 16 | 43.8 | |
IVa | 28 | 55.6 | |
Histological type | |||
Adenocarcinoma | 70 | 52.9 | <0.05 |
Mcinous adenocarcinoma | 5 | 80.0 | |
Papillary carcinoma | 3 | 33.3 | |
Anatomical distribution | |||
Intrahepatic | 20 | 30.0 | 0.267 |
Perihilar | 31 | 46.9 | |
Distal | 27 | 65.4 | |
Lymph node invasion | |||
Present | 47 | 54.7 | 0.494 |
Absent | 31 | 52.0 | |
Differentiation | |||
Well/moderately | 36 | 45.9 | 0.068 |
Poorly/undifferentiated | 42 | 61.0 | |
Metastasis after surgery | |||
+ | 44 | 52.3 | 0.191 |
− | 34 | 55.9 | |
Serum CEA level | |||
>5 ng/ml | 45 | 47.2 | 0.699 |
≤5 ng/ml | 33 | 59.5 | |
Serum CA19-9 level | |||
>37 U/ml | 48 | 52.1 | 0.312 |
≤37 U/ml | 30 | 56.7 | |
HBV infection | |||
+ | 40 | 50.0 | 0.249 |
− | 38 | 57.0 | |
SFRP1 expression | |||
Negative | 52 | 73.1 | <0.0001 |
Positive | 26 | 15.4 | |
β-catenin expression | |||
Negative | 25 | 20 | <0.01 |
Positive | 53 | 69.8 |