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. 2014 Mar 3;9(3):e90308. doi: 10.1371/journal.pone.0090308

Table 4. Univariate analysis of clinicopathologic features for overall survival of 78 patients with biliary tract cancer.

Characteristics n Survival rate (%) P
Gender
Male 34 54.3 0.693
Female 44 53.5
Age(year)
<60 32 41.9 0.984
≥60 46 61.7
TNM stage
I 10 54.5 0.365
II 24 58.3
III 16 43.8
IVa 28 55.6
Histological type
Adenocarcinoma 70 52.9 <0.05
Mcinous adenocarcinoma 5 80.0
Papillary carcinoma 3 33.3
Anatomical distribution
Intrahepatic 20 30.0 0.267
Perihilar 31 46.9
Distal 27 65.4
Lymph node invasion
Present 47 54.7 0.494
Absent 31 52.0
Differentiation
Well/moderately 36 45.9 0.068
Poorly/undifferentiated 42 61.0
Metastasis after surgery
+ 44 52.3 0.191
34 55.9
Serum CEA level
>5 ng/ml 45 47.2 0.699
≤5 ng/ml 33 59.5
Serum CA19-9 level
>37 U/ml 48 52.1 0.312
≤37 U/ml 30 56.7
HBV infection
+ 40 50.0 0.249
38 57.0
SFRP1 expression
Negative 52 73.1 <0.0001
Positive 26 15.4
β-catenin expression
Negative 25 20 <0.01
Positive 53 69.8