Effects of systemic indomethacin (INDO, 5 mg/kg, IP) and trilostane (TRI, 15-60 mg/kg, IP) on startle reflex (A-C) and %PPI (B-D) in relation to the gating deficits induced by systemic apomorphine (APO, 0.25 mg/kg, SC). INDO and TRI doses are indicated in mg/kg. VEH, vehicle of TRI and INDO; SAL, saline. Values are expressed as mean ± S.E.M., N= 7-17/group. #, P<0.05 vs rats treated with VEH and APO; °, P<0.05, °°, P<0.01 vs rats treated with TRI 15 and APO (pretreatment x treatment interaction). Main effects are not indicated. For further details, see text.