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. 2014 Mar 3;9(3):e90814. doi: 10.1371/journal.pone.0090814

Table 4. Anatomical structures that showed significant group differences of annualised volume change (FDR-corrected p0.05). Per group mean and S.D. (in %), univariate between-subjects effects, and pairwise post-hoc Bonferroni test results.

Dependent Variable bvFTD AD CON F(2,36) bvFTD vs CON AD vs CON bvFTD vs AD
Grey Matter
Frontal Lobe
LOFGGM –5.57 (4.5) –2.1 (1.77) –0.99 (1.65) 7.74 * n.s. *
Temporal Lobe
Hippocampus & Amygdala –3.61 (3.24) –3.09 (1.62) –0.95 (0.78) 4.37 * n.s. n.s.
Insula –3.59 (2.85) –2.37 (1.25) –0.73 (0.88) 6.27 * n.s. n.s.
White Matter
Frontal Lobe
FLWM –3.7 (2.57) –2.35 (1.21) –0.7 (1.4) 7.58 * n.s. n.s.
SFGWM –3.84 (2.97) –2.56 (1.35) –0.74 (1.49) 6.20 * n.s. n.s.
PreGWM –3.24 (3.06) –1.84 (2.63) 0.75 (2.82) 5.88 * n.s. n.s.
IFGWM –4.35 (3.28) –3.05 (1.55) –1.26 (1.05) 5.37 * n.s. n.s.
MFGWM –3.29 (2.7) –2.02 (1.08) –0.91 (1.02) 4.98 * n.s. n.s.
MOFGWM –5.46 (2.72) –3.46 (3.46) –2.04 (1.46) 4.75 * n.s. n.s.
Temporal Lobe
MTGWM –2.64 (1.24) –2.08 (0.97) –0.76 (0.47) 10.83 * * n.s.
TLWM –3.75 (2.03) –2.85 (1.25) –0.88 (0.86) 10.65 * * n.s.
ITGWM –5.3 (3.29) –3.87 (2.25) –0.99 (1.3) 8.65 * n.s. n.s.
STGWM –3.9 (2.91) –3.43 (2.87) –0.63 (1.72) 5.04 * n.s. n.s.
FGWM –3.56 (3.26) –1.77 (1.3) –1.12 (0.77) 4.25 n.s. n.s. n.s.
PHGWM –6.81 (6.79) –5.59 (2.34) –1.55 (1.35) 4.24 * n.s. n.s.

n.s.  =  not significant; *  =  p0.05, corrected for multiple comparisons.