Table 4. Anatomical structures that showed significant group differences of annualised volume change (FDR-corrected p0.05). Per group mean and S.D. (in %), univariate between-subjects effects, and pairwise post-hoc Bonferroni test results.
Dependent Variable | bvFTD | AD | CON | F(2,36) | bvFTD vs CON | AD vs CON | bvFTD vs AD |
Grey Matter | |||||||
Frontal Lobe | |||||||
LOFGGM | –5.57 (4.5) | –2.1 (1.77) | –0.99 (1.65) | 7.74 | * | n.s. | * |
Temporal Lobe | |||||||
Hippocampus & Amygdala | –3.61 (3.24) | –3.09 (1.62) | –0.95 (0.78) | 4.37 | * | n.s. | n.s. |
Insula | –3.59 (2.85) | –2.37 (1.25) | –0.73 (0.88) | 6.27 | * | n.s. | n.s. |
White Matter | |||||||
Frontal Lobe | |||||||
FLWM | –3.7 (2.57) | –2.35 (1.21) | –0.7 (1.4) | 7.58 | * | n.s. | n.s. |
SFGWM | –3.84 (2.97) | –2.56 (1.35) | –0.74 (1.49) | 6.20 | * | n.s. | n.s. |
PreGWM | –3.24 (3.06) | –1.84 (2.63) | 0.75 (2.82) | 5.88 | * | n.s. | n.s. |
IFGWM | –4.35 (3.28) | –3.05 (1.55) | –1.26 (1.05) | 5.37 | * | n.s. | n.s. |
MFGWM | –3.29 (2.7) | –2.02 (1.08) | –0.91 (1.02) | 4.98 | * | n.s. | n.s. |
MOFGWM | –5.46 (2.72) | –3.46 (3.46) | –2.04 (1.46) | 4.75 | * | n.s. | n.s. |
Temporal Lobe | |||||||
MTGWM | –2.64 (1.24) | –2.08 (0.97) | –0.76 (0.47) | 10.83 | * | * | n.s. |
TLWM | –3.75 (2.03) | –2.85 (1.25) | –0.88 (0.86) | 10.65 | * | * | n.s. |
ITGWM | –5.3 (3.29) | –3.87 (2.25) | –0.99 (1.3) | 8.65 | * | n.s. | n.s. |
STGWM | –3.9 (2.91) | –3.43 (2.87) | –0.63 (1.72) | 5.04 | * | n.s. | n.s. |
FGWM | –3.56 (3.26) | –1.77 (1.3) | –1.12 (0.77) | 4.25 | n.s. | n.s. | n.s. |
PHGWM | –6.81 (6.79) | –5.59 (2.34) | –1.55 (1.35) | 4.24 | * | n.s. | n.s. |
n.s. = not significant; * = p0.05, corrected for multiple comparisons.