Table 1. Baseline characteristics, stratified by IGR status and the EZSCAN value.
| Glucose regulation status | EZSCAN value | |||
| Variable | NGT | IGR | < Median | ≥ Median |
| (n = 3486) | (n = 2046) | (n = 2611) | (n = 2921) | |
| Age, years | 46.5±8.8 | 50.6±8.7* | 44.6±8.1 | 51.0±8.7† |
| Male | 2244 (64.4) | 1384 (67.6)* | 1698 (65.0) | 1930 (66.1) |
| Body mass index, kg/m2 | 25.0±3.4 | 25.9±3.3* | 24.5±3.2 | 26.0±3.4† |
| Waist circumference, cm | 85.5±10.5 | 88.5±10.0* | 84.2±10.2 | 88.7±10.1† |
| Current smoking | 1117 (32.0) | 628 (30.7) | 799 (30.6) | 946 (32.4) |
| Family history of diabetes | 741 (21.3) | 435 (21.3) | 571 (21.9) | 605 (20.7) |
| Family history of CVD | 737 (21.1) | 406 (19.8) | 541 (20.7) | 602 (20.6) |
| Heart rate | 70±10 | 71±10* | 70±10 | 71±10† |
| Systolic blood pressure, mmHg | 119±17 | 126±19* | 114±14 | 128±18† |
| Diastolic blood pressure, mmHg | 79±12 | 82±12* | 77±10 | 83±12† |
| Mean arterial pressure, mmHg | 92±13 | 97±14* | 89±11 | 98±14† |
| Triglycerides, mmol/l | 1.78±1.67 | 2.15±2.01* | 1.84±1.78 | 1.98±1.84† |
| HDL cholesterol, mmol/l | 1.25±0.34 | 1.19±0.32* | 1.24±0.34 | 1.21±0.33† |
| Fasting glucose, mmol/l | 5.24±0.41 | 5.99±1.30* | 5.40±0.80 | 5.62±1.02† |
| Postprandial glucose, mmol/l | 6.19±0.93 | 9.17±2.12* | 7.02±1.87 | 7.54±2.20† |
| Estimated GFR, ml/min per 1.73 m2 | 111 (98–127) | 112 (99–127) | 114 (101–129) | 110 (97–126)† |
| EZSCAN value, % | 25 (23–45) | 27 (24–50)* | 24 (22–24) | 45 (28–54)† |
Values are mean ± SD, n (%), or median (interquartile range). Normal variables were compared using the Student t test, and non-normal variables were logistically transformed and compared using the Student t test. Categorical variables were compared using the chi-square test.
NGT, normal glucose tolerance; IGR, impaired glucose regulation; CVD, cardiovascular disease; HDL cholesterol, high-density lipoprotein cholesterol; GFR, glomerular filtration rate.
* P<0.05 vs. NGT group.
†
P<0.05 vs. < Median EZSCAN value group.