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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Eur J Immunol. 2013 Oct 20;44(1):239–250. doi: 10.1002/eji.201343774

Figure 4. TCR and CD8 dissociate from pMHC with fast 2D off-rates.

Figure 4

Semi-log plots of lifetime distributions of pMHC bonds with TCR (A, other TCRs are shown in Supporting Information Fig. 2F–J) or CD8 (B) measured by thermal fluctuation. The off-rate was calculated from the negative slope of linear regression. Error bars represent SEM. The high values summarized in (C) show fast dissociation kinetics.