Table 3.
Prevalence of abnormal liver chemistry test and the effect of a gluten-free diet in patients with celiac disease
Reference | Cases | Female (n, %) | Age (range) yrs | Abnormal liver test (n, %) | Response to GFD (n, %) | Time on GFD |
---|---|---|---|---|---|---|
Bardella4 | 158 | 127, 80% | 18-68 | 67, 42% | 60/67, 90% | 6 months |
Hagander6 | 74 | 43, 58% | 14-73 | 29/53, 55% | N/A* | N/A |
Bonamico7 | 65 | 43, 66% | 0.5-18 | 37, 60% | N/A | N/A |
Jacobsen19 | 132 | 64, 48% | 25-86 | 62, 47% | 24/32, 75% | 2 years |
Dickey21 | 129 | 88, 68% | 17-88 | 17, 13% | 15/17, 88% | 6-12 months |
Transaminase levels fell significantly 2.5-8 wks after starting a GFD