Table 1.
Characteristics of Individual Studies
Study and PEDro Score |
Sample Size |
Experimental Intervention |
Duration, timing, and frequency of intervention |
|||||
---|---|---|---|---|---|---|---|---|
Exp | Con | Control Intervention | Outcome tool | Results and p values | Hedge's g | |||
Cheema 20077 8 |
24 | 25 | Strength training | No intervention | 12 wk, during dialysis, 3×/wk | CT | No change in thigh muscle CSA; p=0.40 | 0.078 |
Chen 201026 6 |
22 | 22 | Strength training | Stretching exercises with light resistance bands | 24 wk, during dialysis, 2×/wk | DXA | Leg lean mass changed; p<0.001 | 0.323 |
Dong 201121 5 |
10 | 12 | Strength training and nutritional supplement | Nutritional supplement alone | 6 mo, 3 sets of 12 reps of 1 RM; just before dialysis on dialysis day | DXA | Leg lean mass did not change significantly; p=0.33 | 0.146 |
Johansen 200625 7 |
20 | 20 | Strength training | Placebo nandrolone | 12 wk, 2 sets of 10 reps of each exercise during dialysis | MRI | Change in quadriceps muscle area was significant; p=0.02 | 0.362 |
Kopple 200627 4 |
ET-10 ST-15 EST-12 |
14 | Endurance training, Strength training Endurance and strength training | No exercises | 21 wk, ET-during first 60 min of dialysis ST—just before dialysis EST—as above, 3×/wk | DXA, BIS | Significant change in FFM between pre and post measurements in the ET, ST, EST and controls as measured with DXA, p<0.05 Non-significant when measured with BIS for the three exercising groups combined |
BIS: 0.724; DXA: 0.527 BIS: 0.144; DXA: 0.059 BIS: 0.124; DXA: 0.235 |
Exp=experimental; Con=control; CT=computerized tomography; CSA=cross-sectional area; DXA=dual energy X-ray absorptiometry; RM=repetition maximum; MRI=magnetic resonance imaging; BIS=bioelectrical impedance spectroscopy; FFM=fat-free mass; ET=endurance training; ST=strength training; EST=endurance and strength training.