Table 1.
Characteristic | Mean (SD) | No. (%) |
Female | … | 15 (42.9) |
Age, y | 11.1 (2.6) | … |
CF genotype | ||
F508del/F508del | … | 14 (40) |
F508del/other | … | 15 (43) |
Other/other | … | 6 (17) |
FVC % predicted | 95.5 (17.6) | … |
FEV1 % predicted | 95.3 (15.0) | … |
FEF25-75 % predicted | 84.7 (25.2) | … |
RV % predicteda | 128.5 (49.8) | … |
RV/TLCa | 27.1 (9.4) | … |
Weight, percentile | 37.7 (24.9) | … |
Height, percentile | 34.9 (25.7) | … |
BMI | 17.3 (2.3) | … |
BMI, percentile | 42.3 (25.0) | … |
Pseudomonas aeruginosab | … | 6 (17) |
Staphylococcus aureusb | … | 16 (46) |
CF = cystic fibrosis; FEF25-75 = midvolume forced expiratory flow; RV = residual volume; TLC = total lung capacity.
RV and RV/TLC were available from 28 of 35 subjects.
Respiratory culture data were available from 32 of 35 subjects (91%) who expectorated induced sputum samples for microbial analysis at their baseline visit.