Table 3.
Comparison of prediction performance between the SITS SICH risk score and the extended risk score
| Odds ratio (95% CI) per point | Hosmer-Lemeshow statistic | P | AUC (95% CI) | Difference between areas | P | Net reclassification improvement | P | |
|---|---|---|---|---|---|---|---|---|
| SICH per NINDS |
|
|
|
|
|
|
|
|
| SITS SICH risk score |
1.35 (1.11-1.64) |
1.72 |
0.887 |
0.624 (0.533-0.714) |
- |
- |
- |
- |
| Extended risk score |
1.30 (1.15-1.46) |
4.30 |
0.745 |
0.704 (0.618-0.791) |
0.081 |
0.015 |
22.3% |
0.011 |
| SICH per ECASS II |
|
|
|
|
|
|
|
|
| SITS SICH risk score |
1.34 (1.08-1.68) |
3.25 |
0.661 |
0.612 (0.503-0.721) |
- |
- |
- |
- |
| Extended risk score |
1.30 (1.13-1.49) |
4.23 |
0.752 |
0.703 (0.611-0.796) |
0.091 |
0.016 |
21.2% |
0.018 |
| SICH per SITS-MOST |
|
|
|
|
|
|
|
|
| SITS SICH risk score |
1.49 (1.14-1.94) |
2.10 |
0.835 |
0.678 (0.563-0.793) |
- |
- |
- |
- |
| Extended risk score | 1.33 (1.12-1.58) | 6.45 | 0.488 | 0.723 (0.622-0.824) | 0.044 | 0.293 | 24.5% | 0.024 |
AUC indicates area under the receiver operating characteristic curve; CI: confidence intervals; ECASS: The European-Australasian Cooperative Acute Stroke Study; NINDS: National Institute of Neurological Disorders and Stroke; SICH: symptomatic intracerebral hemorrhage; SITS-MOST: the Safe Implementation of Thrombolysis in Stroke - Monitoring Study.