Table III.
Effect of melatonin on IVF and development rate of mouse embryos, in-vitro
| Melatonin concentrations | No. of two-cell (%) | No. of morula (%) | No. of blastocyst (%) |
|---|---|---|---|
| 100 M | 100 (65.78) | 86 ± 7.8 (86) | 84 ± 6.9 (84) |
| 0 (control) | 103 (80.62) | 88 ± 8.7 (85.43) | 84 ± 7.5 (81.55) |
| 0 (vehicle) | 113 (77.93) | 104 ± 12.3 (84.55) | 102 ± 11 (82.92) |
| 10 nM | 118 (51.98) | 111 ± 12.5 (94)b | 109 ± 11.7 (92.37)c |
| 100 nM | 141 (71.57) | 129 ± 14.6 (91.4)b | 126 ± 14.3 (89.36)c |
| 1 M | 120 (93.75)a | 104 ± 11.6 (86.66) | 99 ± 9.4 (82.5) |
| 10 M | 100 (67.56) | 87 ± 7.6 (87) | 82 ± 6.2 (82) |
a, b within the same column, values with different letters were significantly different in comparison to control group.
a p<0.003, b p<0.034 and c p<0.002.
Chi-square test.