Table 1.
Vaccine groups for challenge study
| Group | No goats | Ad-GFP | Ad-H | Ad-IL-2 | Ad-GMCSF |
|---|---|---|---|---|---|
| A |
4 |
1 × 109 IU |
- |
1 × 109 IU |
1 × 109 IU |
| B |
3 |
2 × 109 IU |
1 × 109 IU |
- |
- |
| C |
3 |
1 × 109 IU |
1 × 109 IU |
1 × 109 IU |
- |
| D |
3 |
1 × 109 IU |
1 × 109 IU |
- |
1 × 109 IU |
| E | 3 | - | 1 × 109 IU | 1 × 109 IU | 1 × 109 IU |
16 outbred, European, male goats, 9 to 12 months of age were vaccinated intra-muscularly with a total of 3 × 109 IU of recombinant adenovirus per animal in a final volume of 1 mL PBS.