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. 2014 Mar 4;4:26. doi: 10.3389/fcimb.2014.00026

Figure 1.

Figure 1

(A–C) Note how the severity of microscopic lesions increases along with the lesion score. Arrowheads indicate foci of granulomatous inflammatory infiltrate. (A) Representative Hematoxylin and Eosin stained section of non-challenged Sham vaccinated control ileum sample (100X). Lesion score = 0. (B) Hematoxylin and Eosin stained section of Silirum® vaccinated and challenged ileum sample (100X). Inset shows Kinouyan's acid-fast stain with a single acid-fast bacillus in center from area labeled with a small star (600X). Lesion score = 3.54. (C) Hematoxylin and Eosin stained section of higher lesion score in a 319 vaccine (group 5) ileum sample (100X). Inset shows Kinouyan's acid-fast stain with multiple acid-fast bacilli from area labeled by a small star (600X). Lesion score = 10.42.