Table 1.
Long ncRNAs involved in neurological disorders.
| Long ncRNA | Regulating | Target | Associated neurological disorder |
|---|---|---|---|
| ANRIL | Transcription | INK4b/ARF/INK4a locus | Neural system tumors |
| BDNF-AS | Transcription | BDNF | Huntington’s disease |
| ncRNA-a | Transcription | CMPK1, TAL1, AURKA | Opitz–Kaveggia syndrome |
| Evf-2 | Transcription | Dlx5/6 | Potentially Rett-syndrome, autism, schizophrenia and epilepsy |
| HTTAS_v1 | Transcription | HTT | Huntington’s disease |
| SCAANT1 | Transcription | Ataxin 7 | Spinocerebellar ataxia 7 |
| 116HG | Transcription | Up-regulation of many genes | Prader–Willi syndrome |
| ATXN8OS | mRNA processing | MBLN1 | Spinocerebellar ataxia 8 |
| 17A | mRNA processing | GPR51 | Alzheimer’s disease |
| Gomafu | mRNA processing | DISC1, ERBB4 | Schizophrenia, behavioral abnormalities |
| BACE1-AS | mRNA stability | BACE1 | Alzheimer’s disease |
| BC200 | Translation | FMR1, PABP, HNRNPA2, SYNCRIP | Alzheimer’s disease |
| Antisense Uchl1 | Translation | UCHL1 | Parkinson’s disease |