Table 3.
Case-specific data of SSI patients of malignant musculoskeletal tumors.
| Age/sex | Diagnosis | Site | Surgical procedure | Reconstruction | Duration of surgery (min) | Blood loss (g) | Isolated bacteria from SSI | Treatment for SSI | Oncological outcome/SSI healing | Treatment duration for SSI (month) | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 62/F | Metastatic bone tumor | Sacrum | Marginal resection | Artificial mesh | 355 | 978 | MRSA | Antibiotics, HBOT, surgery | DOD/not healed | 18 |
| 2 | 61/M | Chondrosarcoma | Femur | Wide resection | Pasteurized autograft, plate and screw | 383 | 500 | CNS | Antibiotics, HBOT, surgery | CDF/healed | 12 |
| 3 | 62/M | Metastatic bone tumor (thyroid) | Humerus | Marginal resection | Tumor-prosthesis | 397 | 270 | MSSA | Antibiotics, HBOT, surgery | DOD/healed | 5 |
| 4 | 13/M | Osteosarcoma | Tibia | Wide resection | Tumor-prosthesis Gastrocnemius muscle flap |
445 | 470 | MRSA | Antibiotics, HBOT, surgery | CDF/healed | 9 |
| 5 | 35/M | Osteosarcoma | Pelvis | Hemipelvectomy | Liquid-nitrogen treated autograft, plate and screw, external fixator | 890 | 4090 | CNS | Antibiotics, HBOT, surgery | DOD/not healed | 12 |
| 6 | 61/M | Metastatic bone tumor (kidney) | Femur | Wide resection | Tumor-prosthesis, Sartorius muscle flap | 514 | 600 | MSSA | Antibiotics, surgery (amputation) | AWD/healed | 1 |
| 7 | 45/M | Myxoid liposarcoma | Thigh | Wide resection including Femur | Pasteurized autograft, plate and screw | 680 | 1620 | MRSA | Antibiotics, HBOT, surgery | DOD/not healed | 18 |
| 8 | 79/F | MFH | Buttock | Wide resection | Gluteal artery perforator flap | 145 | 50 | MRSA | Antibiotics, HBOT | DOO/not healed | 9 |
| 9 | 64/M | MFH | Thigh | Marginal resection | None | 508 | 2505 | Pseudomonas aeruginosa | Antibiotics, HBOT, surgery | DOD/not healed | 9 |
| 10 | 82/M | Dedifferentiated liposarcoma | Thigh | Disarticulation of hip | None | 391 | 220 | Enterobacter cloacae | Antibiotics, surgery | CDF/healed | 5 |
| 11 | 45/M | Myxoid liposarcoma | Thigh | Wide resection including Femur | Pasteurized autograft, plate and screw | 550 | 470 | CNS | Antibiotics, HBOT, surgery | CDF/healed | 18 |
| 12 | 75/M | MFH | Lower leg | Wide resection including Tibia | Bone cement, intramedullary nail, Gastrocnemius muscle flap, FTSG | 283 | 255 | CNS | Antibiotics, HBOT, surgery (local flap) | CDF/not healed | 21 |
| 13 | 30/M | MFH | Groin | Wide resection | None | 250 | 105 | Pseudomonas aeruginosa | Antibiotics, HBOT, surgery (rectus abdominis muscle flap) | CDF/not healed | 3 |
| 14 | 70/F | MFH | Thigh | Marginal resection | Gastrocnemius muscle flap, FTSG | 163 | 30 | MSSA | Antibiotics, HBOT, NPWT | CDF/healed | 3 |
| 15 | 59/M | MFH | Thigh | Wide resection | None | 146 | 0 | MSSA | Antibiotics, HBOT, | AWD/healed | 1 |
| 16 | 73/F | Chondrosarcoma | Hand | Marginal resection including metatarsal bone | Iliac autograft, Kirschner wire | 524 | 685 | Enterobacter cloacae | Antibiotics, surgery (forearm flap) | CDF/healed | 20 |
| 17 | 73/F | MFH | Thigh | Wide resection | Free latissimus dorsi flap, STSG | 626 | 190 | MRSA | Antibiotics, HBOT, surgery, NPWT | AWD/healed | 3 |
| 18 | 68/F | Undifferentiated sarcoma | Thigh | Wide resection | STSG | 189 | 30 | MRSA | Antibiotics | CDF/healed | 2 |
MFH: malignant fibrous histiocytoma (pleomorphic undifferentiated sarcoma); FTSG: full-thickness skin graft; STSG: split-thickness skin graft; MSSA: methicillin-sensitive Staphylococcus aureus; mRSA: Methicillin-resistant Staphylococcus aureus; CNS: coagulase-negative staphylococci; HBOT: hyperbaric oxygen therapy; NPWT: negative-pressure wound therapy; CDF: continuous disease free; DOD: died of disease; DOO: died of other cause (Case 8, uterine cervical cancer); AWD: alive with disease.