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The involvement of the adenosinergic system in MEMC-induced antinociception against acetic acid-induced abdominal writhing test in mice. Each column represents the mean ± S.E.M. of six mice. Control (C: 10% DMSO, p.o.), Caffeine (3 mg/kg, i.p.), and MEMC (500 mg/kg, p.o.). ap < 0.001 significantly different from control group; bp < 0.001 significantly different when compared caffeine-treated group; cp < 0.001 when compared to MEMC-treated group.
