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. 2012 Oct 13;2(3):188–197. doi: 10.1016/j.jobcr.2012.10.002

Table 4.

Adjuvant drugs in the treatment of trigeminal neuralgia.

Drug Dosage
Baclofen Oral: initial dose: 5 mg orally 3 times a day for 3 days, then 10 mg orally 3 times a day for 3 days, then 15 mg orally 3 times a day for 3 days, then 20 mg orally 3 times a day. Maintenance dose: 40–80 mg/day in divided doses
Pimozide Dose of 1–2 mg a day in divided doses. The dose may be increased thereafter every other day. Most patients are maintained at less than 0.2 mg/kg per day, or 10 mg/day, whichever is less
Tizanidine 15–20 mg/day in divided doses
Valproate sodium 800–1600 mg/day in divided doses
Racemic ketamine 0.5 mg/kg/day in divided doses
Methadone 80–120 mg/day in divided doses
Topical capsaicin cream 0.25%, 0.75% ointment
Proparacaine 0.5% eye drops instilled on the affected side