Table 1.
Control | Resveratrol | Longevinex | |
---|---|---|---|
Coronary flow (mL/min) | |||
Baseline | 24 ± 2.1 | 25 ± 3.0 | 24 ± 2.4 |
60 min rep. | 22 ± 2.3 | 24 ± 2.5 | 23 ± 3.1 |
120 min rep. | 23 ± 2.0 | 24 ± 2.8 | 25 ± 1.9 |
Aortic flow (mL/min) | |||
Baseline | 51 ± 2.3 | 53 ± 4.0 | 52 ± 3.8 |
60 min rep. | 25 ± 3.2 | 35 ± 3.7 | 38 ± 2.7 |
120 min rep. | 8.5 ± 2.7 | 24 ± 3.2 | 26 ± 3.5 |
LVDP (mm Hg) | |||
Baseline | 116 ± 6 | 117 ± 7 | 119 ± 9 |
60 min rep. | 80 ± 5 | 98 ± 5 | 101 ± 6 |
120 min rep. | 54 ± 7 | 84 ± 7 | 86 ± 5 |
LVmaxdp/dt (mm Hg/sec) | |||
Baseline | 3056 ± 48 | 1845 ± 45 | 1028 ± 56 |
60 min rep. | 1689 ± 65 | 2356 ± 33 | 1754 ± 39 |
120 min rep. | 1206 ± 38 | 1877 ± 62 | 2012 ± 32 |
Infarct size (infarct area/area of risk) | |||
Baseline | 3 ± 2 | 2.8 ± 1.2 | 2.1 ± 0.8 |
120 min rep. | 36 ± 4 | 19 ± 3 | 17 ± 2 |
Apoptosis (%) | |||
Baseline | 1 ± 1 | 1 ± 0.8 | 1 ± 0.7 |
120 min rep. | 22 ± 3 | 9 ± 2 | 8 ± 2 |