Table 2.
Incidence of cardiovascular events and overall mortality by cystatin C and serum creatinine, categorized by tertiles.
| Cystatin C | Creatinine | |||||
|---|---|---|---|---|---|---|
| Tertile 1 | Tertile 2 | Tertile 3 | Tertile 1 | Tertile 2 | Tertile 3 | |
| Participants number | 59 | 60 | 61 | 59 | 56 | 65 |
| Persons/year | 166 | 196 | 163 | 198 | 151 | 177 |
| Total cardiovascular events | ||||||
| Participants number | 13 | 17 | 23 | 16 | 15 | 22 |
| Incidence/1000 persons-year | 78 | 87 | 141 | 81 | 99 | 124 |
| HR | 0.782 (0.363–1.688) | 0.743 (0.381–1.449) | — | 0.802 (0.401–1.602) | 0.715 (0.345–1.478) | — |
| Fatal cardiovascular events | ||||||
| Participants number | 0 | 2 | 10 | 1 | 4 | 7 |
| Incidence/1000 persons-year | 0 | 10 | 61 | 5 | 26 | 39 |
| HR | 0 | 0.198 (0.040–0.987) | — | 0.126 (0.013–1.265) | 0.403 (0.093–1.740) | — |
| Non-fatal cardiovascular events | ||||||
| Participants number | 13 | 15 | 13 | 15 | 11 | 15 |
| Incidence/1000 persons-year | 78 | 77 | 80 | 76 | 73 | 85 |
| Total mortality | ||||||
| Persons-year | 166 | 199 | 176 | 198 | 151 | 192 |
| Participants number | 1 | 2 | 18 | 2 | 5 | 14 |
| Incidence/1000 persons-year | 6 | 10 | 102 | 10 | 33 | 73 |
| HR | 0.060 (0.008–0.447) | 0.094 (0.022–0.406) | — | 0.178 (0.039–0.805) | 0.329 (0.115–0.442) | — |
| Renal events | ||||||
| Persons-year | 166 | 197 | 166 | 198 | 151 | 177 |
| Participants number | 0 | 5 | 6 | 0 | 2 | 9 |
| Incidence/1000 persons-year | 0 | 25 | 36 | 0 | 13 | 51 |
| HR | 0 | 0.463 (0.095–2.254) | — | 0 | 0.142 (0.035–0.577) | — |
Event risks were evaluated in Cox proportional model, adjusted for age, gender, BMI, previous cardiovascular event, and tobacco consumption. Values in bold letters means that P < 0.005; HR: hazard risk.