Table 3.
Group 1 (n=18) | Group 2 (n=18) | Group 3 (n=18) | P-value | |
---|---|---|---|---|
Baseline AST (U/L) | 1,521±2,320*,** | 260±185 | 55±49 | 0.004 |
451 (35–9,597) | 281 (25–670) | 36 (14–192) | ||
AST max (U/L) | 3,275±3,001*,** | 394±122 | 60±49 | 0.001 |
2,205.5 (1,077–12,261) | 376.5 (236–670) | 43.5 (14–192) | ||
Baseline ALT (U/L) | 810±954*,** | 159±131 | 43±45 | 0.0001 |
389.5 (19–3,215) | 106 (12–384) | 29 (9–197) | ||
ALT max (U/L) | 1,736±1,378*,** | 227±132 | 44±44 | 0.001 |
1,394 (502–6,243) | 236 (58–443) | 29 (9–197) | ||
Baseline LDH (U/L) | 2,058±2,398*,** | 541±355 | 249±131 | 0.001 |
1,057 (255–5,264) | 403.5 (175–1,301) | 230.5 (93–576) | ||
LDH max (U/L) | 4,425±3,199*,** | 831±310 | 266±141 | 0.001 |
3,862 (1,544–14,679) | 864.5 (564–1,408) | 241.5 (111–576) |
Notes: Data are expressed as mean ± standard deviation or median (minimum–maximum).
P<0.05 versus Group 2;
P<0.05 versus Group 3.
Abbreviations: AST, aspartate aminotransferase; ALT, alanine aminotransferase; LDH, lactic dehydrogenase.