Table 2.
Features of Reversal of IHH
| Men |
Women |
|||
|---|---|---|---|---|
| % or Mean (range) | n | % or Mean (range) | n | |
| Spontaneous fertility, number of subjects | 7 | a | 2 | a |
| Normal LH pulse frequency and amplitude | 93% | 25/27 | 25% | 1/4 |
| Mean frequency, pulses/12 h | 6.7 (3–13) | 25 | 10 | |
| Mean amplitude, IU/L | 1.8 (0.5–4.6) | 25 | 1.5 | |
| Normalization of testosterone | 66% | 25/38 | — | |
| Testosterone at baseline, ng/dL | 48 (13–132) | 23 | — | |
| Testosterone at first detection of reversal, ng/dL | 379 (254–764) | 25 | — | |
| Highest testosterone achieved, ng/dL | 451 (257–918) | 25 | — | |
| Testicular growth | 97% | 28/29 | — | |
| Mean TV at baseline, mL | 7.4 (2–17.5) | 28 | — | |
| Mean TV at first detection of reversal, mL | 14.0 (6–25) | 28 | — | |
| Highest mean TV achieved, mL | 15.3 (8–25) | 28 | — | |
| Menstrual cyclicity | — | 60% | 3/5 | |
Abbreviation: TV, testicular volume. —, not applicable.
a
Unknown how many subjects sought fertility.