Table 2.
Demographic data and clinical characteristics of patients included in the study
| nAMD (n = 83) | Controls > 70 years (n = 24) | Controls < 70 years (n = 90) | P-value | Test | |
|---|---|---|---|---|---|
| Median Age in Years (min-max) |
76.0 (63–92) |
76.0 (70–85) |
53.0 (30–69) |
0.001 |
Kruskal-Wallis test |
| Male % |
45 |
38 |
37 |
0.260 |
Pearson Chi-square test |
| Female % |
55 |
62 |
63 |
|
|
| Smoking habits: |
|
|
|
|
|
| Current smokers, (% yes) |
24 |
13 |
14 |
0.650 |
Pearson Chi-square test |
| Former smokers (% yes) |
40 |
33 |
41 |
|
|
| Never smokers (% yes) |
34 |
50 |
43 |
|
|
| Alcohol intake |
|
|
|
|
|
| Above recommended (% yes) |
17 |
14 |
13 |
0.646 |
Pearson Chi-square test |
| BMI (median, IQR), kg/m2 |
25.5 (23.0;28.3) |
26.1 (22.3;27.9) |
24.5 (21.9;28.5) |
0.757 |
Kruskal-Wallis test |
| Plasma concentration of CCL11 (median, IQR) pg/ml | 516 (342;721) | 418 (275;840) | 361 (240;503) | 0.001 | Kruskal-Wallis test |
The table shows Demographic data and clinical characteristics of patients in whom plasma concentration of CCL11 was measured. Difference among groups is calculated using Kruskal-Wallis test and Pearson Chi square test. P-values are given.
AMD Age-related Macular Degeneration, nAMD neovascular AMD, IQR Inter Quartile Range, BMI Body Mass Index.