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. 2014 Feb 11;2014:504279. doi: 10.1155/2014/504279

Table 2.

Patients with acne tend to develop major depression and commit suicide in both genders.

ICD-9-CM 706.x Non-ICD-9-CM 706.x P
n n
Men
Major depression (296.2 + 296.3)
 + 101 (0.61) 1851 (0.39) <0.0001
 − 16467 (99.39) 477419 (99.61)
Suicide (E950–E959)*
 + 1 (0.01) 23 (0.00) 0.5577
 − 16567 (99.99) 479247 (100.00)
Women
Major depression (296.2 + 296.3)
 + 261 (0.85) 3453 (0.73) 0.0142
 − 30282 (99.15) 470166 (99.27)
Suicide (E950–E959)*
 + 6 (0.02) 45 (0.01) 0.1281
 − 30537 (99.98) 473574 (99.99)
Combined group
Major depression (296.2 + 296.3)
 + 362 (0.77) 5304 (0.56) <0.0001
 − 46749 (99.23) 947585 (99.44)
Suicide (E950–E959)*
 + 7 (0.01) 68 (0.01) 0.0900
 − 47104 (99.99) 952821 (99.99)

*Fisher's exact test.