. Author manuscript; available in PMC: 2015 Aug 1.

Published in final edited form as: Magn Reson Med. 2013 Sep 4;72(2):534–545. doi: 10.1002/mrm.24927

Table 1.

Kinetic model parameters used for the simulation studies.

	Baseline	K^trans change	v_e change	v_b change	τ_i change
K^trans (min⁻¹)	0.30	0.05, 0.15, 0.30, 0.45, 0.60	0.30	0.30	0.30
v_e	0.15	0.15	0.10, 0.20, 0.30, 0.40, 0.50	0.15	0.15
v_b	0.06	0.06	0.06	0.02, 0.05, 0.08, 0.11, 0.14	0.06
τ_i (s)	0.2	0.2	0.2	0.2	0.10, 0.30, 0.50, 0.70, 0.90