Table 1. Baseline Characteristics of the Study Population by Gender.
| All (N = 7899) | Women (N = 3970, 50.3%) | Men (N = 3929, 49.7%) | |
| Age (years) | 47.8 (21.8) | 46.9 (21) | 48.8 (22.5) |
| Cardiovascular risk factors | |||
| Current smoker (%) | 2060 (26.1%) | 817 (20.6%) | 1243 (31.6%) |
| Former smoker (%) | 1637 (20.7%) | 555 (14%) | 1081 (27.5%) |
| Hypertension (%) | 3522 (44.6%) | 1461 (36.8%) | 2061 (52.5%) |
| Diabetes (%) | 403 (5.1%) | 188 (4.7%) | 215 (5.5%) |
| Clinical parameters | |||
| Body mass index (kg/m2) | 26.0 (5.5) | 25.4 (6.3) | 26.5 (4.8) |
| Systolic BP (mmHg) | 133 (27) | 129 (26) | 136 (25) |
| Total Cholesterol (mmol/L) | 5.5 (1.4) | 5.4 (1.4) | 5.5 (1.4) |
| HDL Cholesterol (mmol/L) | 1.4 (0.5) | 1.5 (0.5) | 1.2 (0.4) |
| Biomarkers | |||
| cs-cTnI (pg/mL) | 3.9 (9.0) | 3.6 (9.7) | 4.1 (7.8) |
| hs-cTnI (pg/mL) | 3.0 (2.6) | 2.5 (2.1) | 3.6 (3.0) |
| ss-cTnI (pg/mL) | 2.8 (3.0) | 2.5 (2.6) | 3.2 (3.2) |
| CRP (mg/L) | 1.1 (1.9) | 1.1 (1.9) | 1.1 (1.8) |
| NT-proBNP (pg/mL) | 42.1 (59.0) | 55.0 (61.2) | 28.7 (48.4) |
| Incident Outcome | |||
| All-cause death (%) | 810 (10.3%) | 258 (6.5%) | 552 (14%) |
| Fatal MI (%) | 86 (1.1%) | 22 (0.6%) | 64 (1.6%) |
| MI (%) | 277 (3.5%) | 69 (1.7%) | 208 (5.3%) |
| Stroke (%) | 299 (3.8%) | 93 (2.3%) | 206 (5.2%) |
| Heart failure (%) | 505 (6.4%) | 221 (5.6%) | 284 (7.2%) |
| CVD (%) | 770 (9.8%) | 217 (5.5%) | 553 (14.1%) |
| MACE (%) | 1074 (13.6%) | 372 (9.4%) | 702 (17.9%) |
Persons with prevalent MACE and pregnant women have been excluded. Binary variables are shown in absolute counts and percentages. For continuous variables the median and the IQR are shown.
MI = Myocardial infarction, MACE = major adverse cardiac events, BP = blood pressure, HDL = high-density-lipoprotein, CRP = c-reactive protein, NT-proBNP = N-terminal pro-brain natriuretic peptide, IQR = interquartile range, CVD = cardiovascular disease, cs-cTnI = troponin I measured by contemporary-sensitivity assay, hs-cTnI = troponin I measured by high-sensitivity assay, ss-cTnI = troponin measured by super-sensitivity assay