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. 2014 Mar 4;9(3):e90358. doi: 10.1371/journal.pone.0090358

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© 2014 Li et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A and B) TUNEL analysis showing enhanced apoptosis rate in tumor cells when the HepG2-shVASH2 group was compared with the HepG2-shcont group (P<0.05). However, no statistical difference was found in HepG2-VASH2 vs. HepG2-EGFP (P>0.05) at 40× magnification. (C) Western blot analysis showed that p53, Bax, and CC-3 were highly expressed in the HepG2-shVSAH2 group.